14 Principal Scientist Drug Discovery jobs in whatjobs

Principal Scientist, Drug Discovery

50100 Tuwan KES250000 Annually WhatJobs

Posted 20 days ago

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Job Description

full-time
Our client, a leading pharmaceutical innovator, is seeking a highly accomplished Principal Scientist to spearhead groundbreaking drug discovery initiatives. This is a critical role within our Research and Development division, focusing on identifying and validating novel therapeutic targets and developing innovative drug candidates. The successful candidate will leverage extensive experience in molecular biology, pharmacology, and medicinal chemistry to drive research programs from early-stage discovery through to preclinical development. You will lead a team of talented scientists, foster a collaborative research environment, and contribute significantly to our pipeline of life-changing medicines.

Responsibilities:
  • Lead and manage complex drug discovery projects, from target identification and validation to lead optimization.
  • Design and execute in vitro and in vivo studies to evaluate compound efficacy, safety, and pharmacokinetic profiles.
  • Develop and implement cutting-edge assays and experimental models relevant to various therapeutic areas.
  • Analyze and interpret complex experimental data, draw meaningful conclusions, and present findings to senior management and scientific teams.
  • Collaborate closely with medicinal chemists, toxicologists, and other R&D functions to advance drug candidates.
  • Stay abreast of the latest scientific literature, industry trends, and emerging technologies in drug discovery.
  • Mentor and guide junior scientists, fostering their professional development and ensuring high-quality research execution.
  • Contribute to the strategic direction of the R&D portfolio and identify new opportunities for innovation.
  • Prepare and present research findings at international conferences and publish in high-impact peer-reviewed journals.
  • Ensure compliance with all relevant regulatory guidelines and ethical standards.

The ideal candidate will possess a Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline, with a minimum of 10 years of post-doctoral research experience in the pharmaceutical industry or a relevant academic setting. A proven track record of successfully leading drug discovery programs and contributing to the advancement of compounds into clinical development is essential. Expertise in a specific therapeutic area (e.g., oncology, immunology, infectious diseases) is highly desirable. Strong understanding of drug development processes, including ADME/Tox, and regulatory pathways is required. Excellent leadership, communication, and interpersonal skills are crucial for effective team management and cross-functional collaboration. This role is based in Kitale, Trans-Nzoia, KE , and offers a hybrid work model for eligible employees, balancing in-lab research with remote strategic planning and data analysis.
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Principal Scientist, Drug Discovery

80100 Shella KES1200000 Annually WhatJobs

Posted 20 days ago

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full-time
Our client is looking for an exceptional Principal Scientist to lead innovative research initiatives in drug discovery within a fully remote setting. This senior scientific role is crucial for identifying and validating novel therapeutic targets and developing groundbreaking drug candidates. You will be responsible for designing and executing complex research projects, analyzing experimental data, and interpreting results to guide further investigation. The ideal candidate possesses a Ph.D. in a relevant scientific discipline (e.g., Molecular Biology, Pharmacology, Biochemistry) and a minimum of 8-10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry, with a strong focus on early-stage drug discovery. Proven expertise in at least one therapeutic area (e.g., oncology, immunology, infectious diseases) and a deep understanding of target validation, assay development, and hit-to-lead optimization are essential. Experience with various experimental techniques, including genomics, proteomics, cell-based assays, and in vivo models, is required. You will be expected to stay abreast of the latest scientific literature and technological advancements, applying them to solve challenging research questions. Responsibilities include mentoring junior scientists, writing research protocols, preparing scientific publications and presentations, and contributing to patent applications. This is a fully remote position, requiring excellent scientific judgment, critical thinking, and the ability to manage research projects independently and collaboratively with geographically dispersed teams. Strong written and verbal communication skills are vital for scientific reporting and team interactions. We are seeking a highly motivated and creative scientist who is passionate about advancing human health through innovative pharmaceutical research. This is a unique opportunity to make a significant impact on drug discovery pipelines. The job is based in Malindi, Kilifi, KE .
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Principal Scientist - Drug Discovery

00100 Ngong KES250000 Annually WhatJobs

Posted 20 days ago

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Job Description

full-time
Our client, a cutting-edge biotechnology company, is seeking a highly experienced Principal Scientist to lead innovative research in drug discovery. This is a fully remote position, empowering you to drive critical scientific advancements from anywhere. The ideal candidate will possess a deep understanding of molecular biology, genetics, and assay development, with a proven track record of successfully identifying and validating novel drug targets. You will be responsible for designing and executing complex experiments, interpreting results, and contributing to the early-stage pipeline of new therapeutics. This role requires exceptional scientific rigor, strong leadership capabilities, and a passion for translating scientific insights into potential new medicines.

Key Responsibilities:
  • Lead and manage drug discovery research projects, from target identification to lead optimization.
  • Design, develop, and optimize complex biological assays for target validation and compound screening.
  • Investigate novel biological pathways and mechanisms of disease.
  • Analyze and interpret large datasets generated from high-throughput screening and other experimental platforms.
  • Collaborate with medicinal chemists, pharmacologists, and other scientists to advance drug candidates.
  • Stay abreast of the latest scientific literature, technologies, and trends in drug discovery and relevant therapeutic areas.
  • Prepare detailed scientific reports, presentations, and manuscripts for publication and internal use.
  • Mentor and guide junior research scientists, fostering a collaborative and innovative team environment.
  • Contribute to the strategic direction of the drug discovery program.
  • Ensure adherence to laboratory safety protocols and best practices.

Qualifications:
  • PhD in Molecular Biology, Biochemistry, Genetics, Pharmacology, or a related field.
  • Minimum of 10 years of post-doctoral and/or industry experience in drug discovery.
  • Proven expertise in assay development, target validation, and early-stage drug discovery.
  • Hands-on experience with a variety of molecular and cellular biology techniques.
  • Strong understanding of genomics, proteomics, and bioinformatics tools.
  • Demonstrated ability to design and execute complex experiments and interpret complex data.
  • Excellent written and verbal communication skills, including a strong publication record.
  • Proven leadership and team management skills.
  • Ability to work independently, manage multiple projects, and drive research forward in a remote setting.
  • Experience with common therapeutic areas (e.g., oncology, immunology, neurology) is a plus.

This fully remote position offers the opportunity to make a significant impact on scientific research for our client, whose operations are broadly related to the **Ruiru, Kiambu, KE** area, providing a chance to work on groundbreaking discoveries.
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Principal Scientist, Drug Discovery

00200 Ngong KES165000 Annually WhatJobs

Posted 20 days ago

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Job Description

full-time
Our client is recruiting a highly accomplished Principal Scientist to lead critical initiatives within their drug discovery R&D department. This role is exclusively remote, providing the flexibility to conduct groundbreaking research from anywhere. You will be responsible for designing and executing complex biological assays, leading early-stage drug discovery projects, and identifying novel therapeutic targets. Your expertise in areas such as target validation, hit identification, lead optimization, and mechanism of action studies will be invaluable. You will manage project timelines, resources, and budgets, ensuring the successful progression of drug candidates through the preclinical pipeline. Collaboration with medicinal chemists, pharmacologists, toxicologists, and computational biologists will be essential. Responsibilities include developing innovative experimental strategies, troubleshooting complex biological problems, and interpreting diverse datasets. You will also be tasked with preparing scientific manuscripts, patent applications, and presenting findings at international conferences. A Ph.D. in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline, along with a minimum of 8 years of post-doctoral research experience in pharmaceutical or biotechnology settings, is required. Proven leadership in managing research projects and a strong publication record in peer-reviewed journals are essential. Extensive experience with various biological techniques, including high-throughput screening (HTS), cell-based assays, CRISPR technology, and biophysical methods, is highly desirable. Exceptional analytical, critical thinking, and problem-solving skills are mandatory. You must possess excellent written and verbal communication skills to effectively lead and collaborate with a remote global team. If you are a visionary scientist passionate about accelerating the discovery of new medicines and thrive in a remote-first environment, this is an unparalleled opportunity. Contribute your expertise to advancing therapeutic innovations for our client, impacting research relevant to Ruiru, Kiambu, KE .
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Principal Scientist - Drug Discovery

00100 Abothuguchi West KES450000 Annually WhatJobs

Posted 20 days ago

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Job Description

full-time
Our client is seeking a highly innovative and experienced Principal Scientist to lead drug discovery efforts within their fully remote research and development division. This senior role will be instrumental in identifying and validating novel therapeutic targets, designing and executing cutting-edge research programs, and advancing drug candidates through the preclinical pipeline. You will mentor junior scientists, contribute to strategic R&D planning, and collaborate with external research partners and academic institutions. As a remote Principal Scientist, exceptional scientific rigor, strong leadership capabilities, and advanced virtual communication and data-sharing skills are essential.

Key Responsibilities:
  • Lead and design innovative research programs focused on the discovery and development of novel therapeutics.
  • Identify and validate new biological targets for unmet medical needs.
  • Develop and implement robust experimental methodologies for compound screening, lead optimization, and in vivo efficacy studies.
  • Analyze and interpret complex scientific data, drawing meaningful conclusions and making strategic recommendations.
  • Oversee the work of junior scientists and research associates, providing mentorship and guidance.
  • Contribute to the company's scientific strategy and pipeline advancement.
  • Collaborate effectively with internal teams (e.g., medicinal chemistry, pharmacology, DMPK) and external partners.
  • Prepare high-quality scientific reports, publications, and patent applications.
  • Present research findings at scientific conferences and to internal stakeholders.
  • Stay abreast of the latest advancements in relevant scientific fields and translate them into research initiatives.

The ideal candidate will possess a Ph.D. in a relevant biological or biomedical science, with a minimum of 8-10 years of post-doctoral and industry experience in drug discovery. A strong track record of scientific achievement, publications, and successful project leadership is required. Expertise in a specific therapeutic area (e.g., oncology, immunology, neuroscience) is highly desirable. This is a significant opportunity for a visionary scientist to drive groundbreaking research and shape the future of medicine from a completely remote work environment.
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Principal Scientist, Drug Discovery

90200 Gathiruini KES500000 Annually WhatJobs

Posted 18 days ago

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Job Description

full-time
Our client, a cutting-edge biotechnology firm, is seeking an exceptional Principal Scientist to lead critical initiatives in their Drug Discovery division, working entirely remotely. This senior role demands a deep scientific understanding, a proven track record of innovative research, and the ability to guide complex R&D projects from inception to pre-clinical stages. The ideal candidate will possess extensive expertise in medicinal chemistry, molecular biology, or a related discipline, with a strong publication record and a history of successful drug candidate identification. As a remote-first professional, you will be responsible for designing and executing innovative research strategies, developing and validating novel assays, and leading a team of scientists in achieving research objectives. This position requires outstanding leadership, problem-solving, and communication skills, along with a profound understanding of the drug discovery pipeline and regulatory landscape. Key responsibilities include conceptualizing and implementing cutting-edge research programs, interpreting complex experimental data, mentoring junior scientists, and collaborating closely with internal and external stakeholders. You will also play a key role in intellectual property generation and scientific strategy development. A Ph.D. in a relevant scientific discipline (e.g., Chemistry, Biology, Pharmacology) is mandatory, along with a minimum of 10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry. Extensive experience with high-throughput screening, lead optimization, and in vivo pharmacology is highly desirable. Demonstrated success in managing research projects and leading scientific teams in a collaborative, remote environment is essential. We are looking for a visionary scientist who can drive scientific excellence and contribute significantly to the development of transformative therapies.
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Principal Scientist - Drug Discovery

20101 Mwembe KES450000 Annually WhatJobs

Posted 19 days ago

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Job Description

full-time
Our client is seeking a highly accomplished Principal Scientist to lead groundbreaking research initiatives in drug discovery. This fully remote role offers an unparalleled opportunity for a seasoned scientist to contribute to innovative pharmaceutical research from anywhere. You will be instrumental in identifying novel therapeutic targets, designing and executing preclinical studies, and advancing drug candidates through the development pipeline. Your deep expertise in molecular biology, pharmacology, and medicinal chemistry will be essential for driving scientific innovation and contributing to the development of life-changing medicines.

Key Responsibilities:
  • Lead and manage research projects focused on the discovery and development of novel therapeutics.
  • Identify and validate new drug targets using cutting-edge biological techniques and data analysis.
  • Design, execute, and interpret in vitro and in vivo experiments to assess the efficacy and safety of drug candidates.
  • Develop and optimize assays for high-throughput screening and lead optimization.
  • Collaborate with cross-functional teams, including medicinal chemists, pharmacologists, and toxicologists.
  • Analyze and interpret complex biological data, drawing sound conclusions and making informed recommendations.
  • Stay abreast of the latest scientific advancements and emerging technologies in drug discovery and related fields.
  • Mentor and guide junior scientists, fostering a collaborative and productive research environment.
  • Prepare and present research findings to internal teams and external collaborators.
  • Contribute to the preparation of regulatory documents and scientific publications.
  • Manage external research collaborations and vendor relationships.
Qualifications:
  • Ph.D. in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline.
  • Minimum of 8 years of progressive research experience in drug discovery within the pharmaceutical or biotechnology industry.
  • Proven track record of success in identifying and advancing drug candidates.
  • In-depth knowledge of molecular mechanisms of disease and therapeutic intervention strategies.
  • Extensive experience with a variety of biological assays and experimental techniques.
  • Strong analytical and problem-solving skills with a data-driven approach.
  • Excellent leadership, communication, and interpersonal skills, essential for remote team synergy.
  • Ability to work independently, manage multiple complex projects, and meet deadlines in a remote research setting.
  • Experience with bioinformatics and computational biology tools is a plus.
  • A strong publication record in peer-reviewed journals is highly desirable.
This is a unique chance to be at the forefront of scientific discovery and contribute to the development of novel therapies that improve patient outcomes. If you are a passionate and experienced scientist, we encourage you to apply.
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Principal Scientist - Drug Discovery

01002 Ngong KES280000 Annually WhatJobs

Posted 16 days ago

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Job Description

full-time
Our client, a pioneering pharmaceutical company, is seeking a highly accomplished Principal Scientist to lead critical initiatives in drug discovery. This fully remote role requires a visionary scientist with a deep understanding of molecular biology, pharmacology, and medicinal chemistry to drive the identification and development of novel therapeutic agents. You will be responsible for designing and executing complex research programs, managing research teams, and contributing to the company's pipeline of innovative medicines. The ideal candidate possesses a strong scientific background, a proven track record in successful drug discovery projects, and extensive experience in modern research methodologies. You will collaborate with cross-functional teams, including biologists, chemists, and clinical researchers, to advance drug candidates from target identification through preclinical development. This position demands exceptional leadership skills, the ability to mentor junior scientists, and a strong publication record in peer-reviewed journals. Your expertise will be crucial in navigating the challenges of drug discovery and bringing transformative treatments to patients. You will play a pivotal role in shaping the company's research direction and contributing to groundbreaking scientific advancements, all within a collaborative remote setting. The successful applicant will be expected to stay at the forefront of scientific innovation and foster a culture of scientific excellence and collaboration.

Responsibilities:
  • Lead and direct drug discovery research programs from target validation to lead optimization.
  • Design and execute in vitro and in vivo studies to assess compound efficacy and safety.
  • Develop and implement novel approaches for small molecule and/or biologic drug discovery.
  • Manage and mentor a team of research scientists and technicians.
  • Collaborate closely with medicinal chemists, biologists, pharmacologists, and toxicologists.
  • Analyze complex biological and chemical data to identify key insights and guide research directions.
  • Contribute to the development of intellectual property and patent applications.
  • Prepare research reports, presentations, and scientific publications.
  • Stay abreast of the latest scientific literature, technologies, and therapeutic trends.
  • Contribute to strategic planning for the drug discovery pipeline.
  • Ensure compliance with all regulatory guidelines and company policies.
Qualifications:
  • Ph.D. in Pharmacology, Molecular Biology, Biochemistry, Medicinal Chemistry, or a related life science discipline.
  • Minimum of 10 years of progressive experience in pharmaceutical or biotechnology drug discovery.
  • Proven track record of successfully advancing drug candidates through the discovery pipeline.
  • Extensive experience with various drug discovery platforms and technologies.
  • Strong leadership, project management, and team-building skills.
  • Excellent analytical, problem-solving, and critical thinking abilities.
  • Proficiency in data analysis and scientific interpretation.
  • Strong publication record in high-impact peer-reviewed journals.
  • Excellent written and verbal communication skills.
  • Ability to work effectively and independently in a remote research environment.
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Principal Scientist, Drug Discovery

90130 Gathiruini KES550000 Annually WhatJobs

Posted 16 days ago

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full-time
Our client, a leading innovator in pharmaceutical research, is seeking an exceptional Principal Scientist, Drug Discovery to join their advanced, fully remote Scientific Research & Development team. This senior position will play a critical role in shaping the future of our therapeutic pipeline by leading groundbreaking research initiatives. The ideal candidate will possess a distinguished academic record and extensive experience in medicinal chemistry, pharmacology, or a related field, with a strong publication history and a proven ability to drive discovery projects from target identification through to preclinical candidate selection.

Key Responsibilities:
  • Lead and manage multiple drug discovery projects, setting scientific direction and strategic goals.
  • Design and execute complex experimental strategies to identify and validate novel therapeutic targets.
  • Oversee the synthesis, characterization, and optimization of lead compounds using state-of-the-art medicinal chemistry techniques.
  • Collaborate closely with biologists, pharmacologists, and other scientific disciplines to advance drug candidates through the discovery pipeline.
  • Analyze and interpret complex experimental data, drawing sound conclusions and making informed decisions regarding project direction.
  • Develop and implement cutting-edge technologies and methodologies to enhance drug discovery efficiency and success rates.
  • Mentor and guide junior scientists, fostering a collaborative and high-performing research environment.
  • Prepare and present research findings to internal teams, steering committees, and at scientific conferences.
  • Manage intellectual property, including patent filings and publications.
  • Contribute to the strategic planning and business development efforts of the R&D division.

This is a fully remote role, requiring exceptional autonomy, strong leadership, and superior communication skills. Proficiency in data analysis software and a deep understanding of relevant therapeutic areas are essential. Experience with high-throughput screening (HTS), structure-based drug design, and in vivo pharmacology studies is highly valued. The ability to think critically, solve complex scientific problems, and foster collaborative relationships in a virtual setting is paramount. We are seeking a visionary scientist who is passionate about advancing human health.
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Principal Scientist, Drug Discovery

10100 Nyeri Town KES350000 Annually WhatJobs

Posted 11 days ago

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full-time
Our client, an innovative biotechnology firm, is seeking a highly accomplished Principal Scientist, Drug Discovery to lead cutting-edge research and development initiatives from a fully remote position. This senior role demands exceptional scientific leadership, a deep understanding of molecular biology and pharmacology, and a proven track record of successfully advancing drug candidates from discovery through preclinical development. You will be responsible for designing and executing complex research projects, identifying novel therapeutic targets, and developing innovative strategies for drug design and optimization. The ideal candidate will possess extensive experience in leading scientific teams, managing research budgets, and collaborating with internal and external partners to achieve critical research milestones. As a remote-first role, you will leverage advanced digital collaboration tools to manage projects, share findings, and communicate effectively with global teams. Responsibilities include: conceptualizing and leading innovative drug discovery programs; designing and interpreting in vitro and in vivo experiments; characterizing the efficacy and safety of potential drug candidates; managing collaborations with academic institutions and contract research organizations (CROs); writing and presenting research findings at scientific conferences and in peer-reviewed publications; mentoring and developing junior scientists; contributing to the strategic direction of the R&D pipeline; ensuring compliance with all relevant regulatory guidelines and ethical standards. A Ph.D. in Molecular Biology, Pharmacology, Biochemistry, or a related field, with a minimum of 10 years of post-doctoral and industry experience in drug discovery is essential. Strong proficiency in modern molecular and cellular biology techniques, assay development, and data analysis is required. This is a unique opportunity for a pioneering scientist to make a significant impact on human health, working in a flexible, remote setting. The conceptual location for this role is Nyeri, Nyeri, KE , but the position is fully remote.
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