14 Principal Scientist Drug Discovery jobs in whatjobs
Principal Scientist, Drug Discovery
Posted 20 days ago
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Job Description
Responsibilities:
- Lead and manage complex drug discovery projects, from target identification and validation to lead optimization.
- Design and execute in vitro and in vivo studies to evaluate compound efficacy, safety, and pharmacokinetic profiles.
- Develop and implement cutting-edge assays and experimental models relevant to various therapeutic areas.
- Analyze and interpret complex experimental data, draw meaningful conclusions, and present findings to senior management and scientific teams.
- Collaborate closely with medicinal chemists, toxicologists, and other R&D functions to advance drug candidates.
- Stay abreast of the latest scientific literature, industry trends, and emerging technologies in drug discovery.
- Mentor and guide junior scientists, fostering their professional development and ensuring high-quality research execution.
- Contribute to the strategic direction of the R&D portfolio and identify new opportunities for innovation.
- Prepare and present research findings at international conferences and publish in high-impact peer-reviewed journals.
- Ensure compliance with all relevant regulatory guidelines and ethical standards.
The ideal candidate will possess a Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline, with a minimum of 10 years of post-doctoral research experience in the pharmaceutical industry or a relevant academic setting. A proven track record of successfully leading drug discovery programs and contributing to the advancement of compounds into clinical development is essential. Expertise in a specific therapeutic area (e.g., oncology, immunology, infectious diseases) is highly desirable. Strong understanding of drug development processes, including ADME/Tox, and regulatory pathways is required. Excellent leadership, communication, and interpersonal skills are crucial for effective team management and cross-functional collaboration. This role is based in Kitale, Trans-Nzoia, KE , and offers a hybrid work model for eligible employees, balancing in-lab research with remote strategic planning and data analysis.
Principal Scientist, Drug Discovery
Posted 20 days ago
Job Viewed
Job Description
Principal Scientist - Drug Discovery
Posted 20 days ago
Job Viewed
Job Description
Key Responsibilities:
- Lead and manage drug discovery research projects, from target identification to lead optimization.
- Design, develop, and optimize complex biological assays for target validation and compound screening.
- Investigate novel biological pathways and mechanisms of disease.
- Analyze and interpret large datasets generated from high-throughput screening and other experimental platforms.
- Collaborate with medicinal chemists, pharmacologists, and other scientists to advance drug candidates.
- Stay abreast of the latest scientific literature, technologies, and trends in drug discovery and relevant therapeutic areas.
- Prepare detailed scientific reports, presentations, and manuscripts for publication and internal use.
- Mentor and guide junior research scientists, fostering a collaborative and innovative team environment.
- Contribute to the strategic direction of the drug discovery program.
- Ensure adherence to laboratory safety protocols and best practices.
Qualifications:
- PhD in Molecular Biology, Biochemistry, Genetics, Pharmacology, or a related field.
- Minimum of 10 years of post-doctoral and/or industry experience in drug discovery.
- Proven expertise in assay development, target validation, and early-stage drug discovery.
- Hands-on experience with a variety of molecular and cellular biology techniques.
- Strong understanding of genomics, proteomics, and bioinformatics tools.
- Demonstrated ability to design and execute complex experiments and interpret complex data.
- Excellent written and verbal communication skills, including a strong publication record.
- Proven leadership and team management skills.
- Ability to work independently, manage multiple projects, and drive research forward in a remote setting.
- Experience with common therapeutic areas (e.g., oncology, immunology, neurology) is a plus.
This fully remote position offers the opportunity to make a significant impact on scientific research for our client, whose operations are broadly related to the **Ruiru, Kiambu, KE** area, providing a chance to work on groundbreaking discoveries.
Principal Scientist, Drug Discovery
Posted 20 days ago
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Job Description
Principal Scientist - Drug Discovery
Posted 20 days ago
Job Viewed
Job Description
Key Responsibilities:
- Lead and design innovative research programs focused on the discovery and development of novel therapeutics.
- Identify and validate new biological targets for unmet medical needs.
- Develop and implement robust experimental methodologies for compound screening, lead optimization, and in vivo efficacy studies.
- Analyze and interpret complex scientific data, drawing meaningful conclusions and making strategic recommendations.
- Oversee the work of junior scientists and research associates, providing mentorship and guidance.
- Contribute to the company's scientific strategy and pipeline advancement.
- Collaborate effectively with internal teams (e.g., medicinal chemistry, pharmacology, DMPK) and external partners.
- Prepare high-quality scientific reports, publications, and patent applications.
- Present research findings at scientific conferences and to internal stakeholders.
- Stay abreast of the latest advancements in relevant scientific fields and translate them into research initiatives.
The ideal candidate will possess a Ph.D. in a relevant biological or biomedical science, with a minimum of 8-10 years of post-doctoral and industry experience in drug discovery. A strong track record of scientific achievement, publications, and successful project leadership is required. Expertise in a specific therapeutic area (e.g., oncology, immunology, neuroscience) is highly desirable. This is a significant opportunity for a visionary scientist to drive groundbreaking research and shape the future of medicine from a completely remote work environment.
Principal Scientist, Drug Discovery
Posted 18 days ago
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Job Description
Principal Scientist - Drug Discovery
Posted 19 days ago
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Job Description
Key Responsibilities:
- Lead and manage research projects focused on the discovery and development of novel therapeutics.
- Identify and validate new drug targets using cutting-edge biological techniques and data analysis.
- Design, execute, and interpret in vitro and in vivo experiments to assess the efficacy and safety of drug candidates.
- Develop and optimize assays for high-throughput screening and lead optimization.
- Collaborate with cross-functional teams, including medicinal chemists, pharmacologists, and toxicologists.
- Analyze and interpret complex biological data, drawing sound conclusions and making informed recommendations.
- Stay abreast of the latest scientific advancements and emerging technologies in drug discovery and related fields.
- Mentor and guide junior scientists, fostering a collaborative and productive research environment.
- Prepare and present research findings to internal teams and external collaborators.
- Contribute to the preparation of regulatory documents and scientific publications.
- Manage external research collaborations and vendor relationships.
- Ph.D. in Molecular Biology, Pharmacology, Biochemistry, or a related life science discipline.
- Minimum of 8 years of progressive research experience in drug discovery within the pharmaceutical or biotechnology industry.
- Proven track record of success in identifying and advancing drug candidates.
- In-depth knowledge of molecular mechanisms of disease and therapeutic intervention strategies.
- Extensive experience with a variety of biological assays and experimental techniques.
- Strong analytical and problem-solving skills with a data-driven approach.
- Excellent leadership, communication, and interpersonal skills, essential for remote team synergy.
- Ability to work independently, manage multiple complex projects, and meet deadlines in a remote research setting.
- Experience with bioinformatics and computational biology tools is a plus.
- A strong publication record in peer-reviewed journals is highly desirable.
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Principal Scientist - Drug Discovery
Posted 16 days ago
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Job Description
Responsibilities:
- Lead and direct drug discovery research programs from target validation to lead optimization.
- Design and execute in vitro and in vivo studies to assess compound efficacy and safety.
- Develop and implement novel approaches for small molecule and/or biologic drug discovery.
- Manage and mentor a team of research scientists and technicians.
- Collaborate closely with medicinal chemists, biologists, pharmacologists, and toxicologists.
- Analyze complex biological and chemical data to identify key insights and guide research directions.
- Contribute to the development of intellectual property and patent applications.
- Prepare research reports, presentations, and scientific publications.
- Stay abreast of the latest scientific literature, technologies, and therapeutic trends.
- Contribute to strategic planning for the drug discovery pipeline.
- Ensure compliance with all regulatory guidelines and company policies.
- Ph.D. in Pharmacology, Molecular Biology, Biochemistry, Medicinal Chemistry, or a related life science discipline.
- Minimum of 10 years of progressive experience in pharmaceutical or biotechnology drug discovery.
- Proven track record of successfully advancing drug candidates through the discovery pipeline.
- Extensive experience with various drug discovery platforms and technologies.
- Strong leadership, project management, and team-building skills.
- Excellent analytical, problem-solving, and critical thinking abilities.
- Proficiency in data analysis and scientific interpretation.
- Strong publication record in high-impact peer-reviewed journals.
- Excellent written and verbal communication skills.
- Ability to work effectively and independently in a remote research environment.
Principal Scientist, Drug Discovery
Posted 16 days ago
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Job Description
Key Responsibilities:
- Lead and manage multiple drug discovery projects, setting scientific direction and strategic goals.
- Design and execute complex experimental strategies to identify and validate novel therapeutic targets.
- Oversee the synthesis, characterization, and optimization of lead compounds using state-of-the-art medicinal chemistry techniques.
- Collaborate closely with biologists, pharmacologists, and other scientific disciplines to advance drug candidates through the discovery pipeline.
- Analyze and interpret complex experimental data, drawing sound conclusions and making informed decisions regarding project direction.
- Develop and implement cutting-edge technologies and methodologies to enhance drug discovery efficiency and success rates.
- Mentor and guide junior scientists, fostering a collaborative and high-performing research environment.
- Prepare and present research findings to internal teams, steering committees, and at scientific conferences.
- Manage intellectual property, including patent filings and publications.
- Contribute to the strategic planning and business development efforts of the R&D division.
This is a fully remote role, requiring exceptional autonomy, strong leadership, and superior communication skills. Proficiency in data analysis software and a deep understanding of relevant therapeutic areas are essential. Experience with high-throughput screening (HTS), structure-based drug design, and in vivo pharmacology studies is highly valued. The ability to think critically, solve complex scientific problems, and foster collaborative relationships in a virtual setting is paramount. We are seeking a visionary scientist who is passionate about advancing human health.
Principal Scientist, Drug Discovery
Posted 11 days ago
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