16 Principal Research Scientist Drug Discovery jobs in whatjobs
Principal Research Scientist - Drug Discovery
Posted 20 days ago
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Principal Research Scientist, Drug Discovery
Posted 18 days ago
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Key Responsibilities:
- Lead and execute complex research projects focused on identifying and validating new drug targets for various diseases.
- Design and conduct in vitro and in vivo experiments to evaluate the efficacy and safety of potential drug candidates.
- Develop and implement novel biochemical and cellular assays for high-throughput screening and lead optimization.
- Analyze and interpret complex datasets, drawing meaningful conclusions and making strategic recommendations for project progression.
- Collaborate closely with internal cross-functional teams (chemistry, pharmacology, toxicology, clinical development) and external academic partners.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and innovation.
- Contribute to the development of intellectual property, including patent filings and scientific publications.
- Stay current with the latest scientific literature, technological advancements, and competitive landscape in relevant therapeutic areas.
- Prepare and present research findings at internal meetings and external scientific conferences.
- Ensure all research activities are conducted in compliance with ethical guidelines and company standards.
- Ph.D. in Pharmacology, Biochemistry, Molecular Biology, or a related life science discipline from a recognized institution.
- A minimum of 8 years of post-doctoral research experience in drug discovery within the pharmaceutical or biotechnology industry.
- Proven track record of successfully leading research programs and delivering key milestones in drug discovery.
- Extensive experience in assay development, target validation, and preclinical drug evaluation.
- Strong understanding of molecular biology, cell signaling pathways, and disease pathophysiology.
- Proficiency in a variety of biological techniques, including molecular cloning, Western blotting, ELISA, flow cytometry, and cell-based assays.
- Experience with computational biology tools and data analysis software is a plus.
- Excellent problem-solving skills and the ability to think critically and creatively.
- Exceptional written and verbal communication skills, with a strong aptitude for scientific writing and presentation.
- Demonstrated ability to thrive in a fast-paced, collaborative, and remote research environment.
Principal Research Scientist - Drug Discovery
Posted 17 days ago
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Principal Research Scientist, Drug Discovery
Posted 10 days ago
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Location: This is a fully remote position. While the operational hub is in Kisumu, Kisumu, KE , candidates can work from any approved remote location.
Principal Research Scientist (Drug Discovery)
Posted 9 days ago
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Key Responsibilities:
- Lead the design and execution of innovative drug discovery projects.
- Identify and validate novel therapeutic targets using state-of-the-art methodologies.
- Develop and optimize assays for screening and characterization of drug candidates.
- Interpret complex biological and chemical data to guide project progression.
- Collaborate effectively with internal and external partners, including CROs.
- Mentor and guide junior scientists, fostering a culture of scientific excellence.
- Prepare high-quality reports, publications, and presentations.
- Contribute to the strategic direction of the drug discovery portfolio.
- Stay abreast of the latest advancements in relevant scientific fields.
Qualifications:
- PhD in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline.
- 10+ years of post-doctoral research experience in the pharmaceutical industry or biotech.
- Demonstrated success in leading drug discovery programs and advancing candidates through preclinical stages.
- Extensive knowledge of small molecule or biologics drug discovery.
- Proficiency in a wide range of molecular and cellular biology techniques.
- Experience with data analysis and bioinformatics tools.
- Excellent written and verbal communication skills.
- Proven leadership and team management capabilities.
Principal Research Scientist - Drug Discovery
Posted 6 days ago
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Principal Research Scientist - Drug Discovery
Posted 6 days ago
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Job Description
Key Responsibilities:
- Lead and direct research programs focused on identifying and validating novel therapeutic targets for various diseases.
- Design and execute complex in vitro and in vivo experiments to assess compound efficacy and safety.
- Analyze and interpret experimental data, drawing robust conclusions and making strategic recommendations for project progression.
- Collaborate closely with medicinal chemists, biologists, pharmacologists, and toxicologists to advance drug candidates.
- Author high-impact scientific publications and present findings at international conferences.
- Mentor and guide junior scientists and research associates, fostering a collaborative and innovative research environment.
- Stay current with the latest scientific literature, technological advancements, and emerging trends in drug discovery.
- Contribute to the development of intellectual property through patent filings.
- Manage research budgets and resources effectively to ensure project success.
- Contribute to the strategic direction of the R&D pipeline.
- Ph.D. in Pharmacology, Molecular Biology, Biochemistry, or a related life science discipline.
- Minimum of 10 years of progressive research experience in the pharmaceutical or biotechnology industry.
- Demonstrated success in leading drug discovery programs, with at least one candidate successfully progressed into clinical development.
- Expertise in a specific therapeutic area (e.g., oncology, immunology, neuroscience) is highly desirable.
- Proficiency in a broad range of biochemical, cellular, and molecular biology techniques.
- Strong understanding of drug discovery and development processes, including target identification, lead optimization, and preclinical testing.
- Excellent analytical, problem-solving, and critical thinking skills.
- Exceptional written and verbal communication skills, with a proven ability to publish and present complex scientific data.
- Demonstrated leadership and team management capabilities.
- Experience working in a fully remote setting is a plus.
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Principal Research Scientist - Drug Discovery
Posted 20 days ago
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Job Description
Responsibilities:
- Lead the design and execution of complex research projects focused on identifying and optimizing novel drug candidates.
- Develop and implement innovative biochemical and cellular assays to assess compound activity and mechanism of action.
- Analyze and interpret large datasets, drawing insightful conclusions to guide project progression.
- Collaborate closely with internal and external partners, including medicinal chemists, biologists, pharmacologists, and computational scientists.
- Manage project timelines, resources, and budgets effectively within a remote framework.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and innovation.
- Prepare and present research findings to scientific teams, leadership, and at external conferences.
- Contribute to the development of scientific strategy and identify new opportunities for drug discovery.
- Ensure all research activities comply with relevant regulatory guidelines and ethical standards.
- Stay current with the latest scientific literature and technological advancements in drug discovery and relevant therapeutic areas.
- Critically evaluate new technologies and methodologies to enhance our drug discovery capabilities.
- Document experimental procedures and results meticulously in electronic lab notebooks.
- Contribute to the intellectual property portfolio through patent applications and disclosures.
- Ph.D. in Pharmacology, Biochemistry, Molecular Biology, Medicinal Chemistry, or a related life science discipline.
- Minimum of 7 years of progressive research experience in the pharmaceutical or biotechnology industry, with a focus on drug discovery.
- Demonstrated expertise in one or more therapeutic areas (e.g., oncology, immunology, neuroscience).
- Proven track record of successfully advancing drug discovery programs from target identification to preclinical development.
- Extensive experience with a variety of in vitro assay formats (e.g., enzyme assays, cell-based assays, target engagement assays).
- Strong understanding of drug metabolism and pharmacokinetic (DMPK) principles.
- Proficiency in data analysis software and statistical methods.
- Excellent written and verbal communication skills, with experience presenting complex scientific data.
- Demonstrated ability to lead, motivate, and mentor a team of scientists in a remote environment.
- Experience with intellectual property development and patent filings.
- Ability to work independently and collaboratively in a fast-paced, remote setting.
- Published research in reputable scientific journals and/or patents.
Principal Research Scientist - Drug Discovery
Posted 16 days ago
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Responsibilities:
- Lead independent research programs focused on the discovery and development of novel drug candidates.
- Design and execute complex experiments in areas such as target identification, validation, and hit-to-lead optimization.
- Analyze and interpret experimental data, drawing conclusions and proposing next steps.
- Develop and implement new methodologies and technologies to advance drug discovery efforts.
- Mentor and guide junior research scientists, fostering their scientific development.
- Collaborate closely with cross-functional teams, including chemistry, biology, and clinical development.
- Prepare scientific manuscripts, patents, and presentations for internal and external audiences.
- Contribute to the strategic planning and prioritization of research projects.
- Stay abreast of the latest scientific literature and emerging trends in pharmaceutical research.
- Ensure compliance with all safety regulations and laboratory best practices.
- Ph.D. in Molecular Biology, Pharmacology, Biochemistry, Medicinal Chemistry, or a related life science discipline.
- A minimum of 10 years of post-doctoral research experience in the pharmaceutical or biotechnology industry.
- Extensive experience in drug discovery, with a proven track record of bringing compounds through the preclinical stages.
- Deep expertise in at least one major therapeutic area (e.g., oncology, immunology, infectious diseases).
- Proficiency in a range of molecular and cellular biology techniques, assay development, and data analysis.
- Strong understanding of medicinal chemistry principles and drug metabolism.
- Excellent scientific leadership, problem-solving, and critical thinking skills.
- Exceptional written and oral communication skills, with the ability to present complex scientific information clearly.
- Experience mentoring and managing scientific teams.
- Proven ability to work effectively in a collaborative, remote research environment.
Principal Research Scientist, Drug Discovery
Posted 14 days ago
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Job Description
Responsibilities:
- Lead and direct research projects focused on identifying and validating novel drug targets for unmet medical needs across various therapeutic areas.
- Design, optimize, and execute complex in vitro and in vivo experimental studies to evaluate the efficacy and safety of potential drug candidates.
- Develop and implement cutting-edge assays and methodologies to support drug discovery efforts.
- Analyze and interpret complex experimental data, drawing robust conclusions and making critical decisions regarding project direction.
- Supervise, mentor, and develop a team of research scientists and technicians, fostering a collaborative and innovative research environment.
- Author high-impact publications in peer-reviewed journals and present research findings at international scientific conferences.
- Manage research budgets, resources, and timelines effectively to ensure project success.
- Collaborate closely with cross-functional teams, including medicinal chemists, pharmacologists, toxicologists, and clinicians.
- Contribute to the strategic planning and direction of the drug discovery pipeline.
- Maintain a deep understanding of the latest scientific advancements and technological innovations in drug discovery.
- Ensure all research activities comply with ethical standards, regulatory guidelines, and institutional policies.
- Contribute to intellectual property generation through patent applications.
- Build and maintain strong relationships with academic collaborators and key opinion leaders in the field.
Qualifications:
- Ph.D. in Molecular Biology, Pharmacology, Biochemistry, or a closely related life science discipline.
- 10+ years of post-doctoral research experience in drug discovery, with a significant portion in a leadership or principal investigator role within the pharmaceutical or biotech industry.
- Proven track record of successfully leading research programs and delivering key scientific milestones.
- Extensive experience in target identification and validation, assay development, lead optimization, and preclinical drug development.
- Expertise in a specific therapeutic area (e.g., oncology, immunology, neuroscience) is highly desirable.
- Strong understanding of molecular biology techniques, cell-based assays, and relevant analytical methodologies.
- Exceptional scientific judgment, critical thinking, and problem-solving skills.
- Excellent written and verbal communication skills, with a talent for clear and impactful scientific writing and presentation.
- Demonstrated ability to mentor and lead research teams effectively.
- Strong grant writing and proposal development skills.
- Experience with bioinformatics and computational biology tools is a plus.
- Ability to work independently and collaboratively in a demanding research setting.
This is an exceptional opportunity for a visionary scientist to make a significant impact on the future of medicine. If you possess the passion and expertise to drive transformative drug discovery, we encourage you to apply.