36 Principal Pharmaceutical Research Scientist Drug Discovery jobs in whatjobs
Principal Pharmaceutical Research Scientist - Drug Discovery
Posted 20 days ago
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Job Description
Responsibilities:
- Lead and direct research projects focused on the discovery and development of novel pharmaceutical agents.
- Design and execute innovative experimental strategies in areas such as medicinal chemistry, pharmacology, and molecular biology.
- Interpret complex scientific data, identify critical insights, and guide project progression.
- Manage and mentor a team of research scientists, fostering a collaborative and innovative environment.
- Collaborate effectively with internal departments, including clinical research, regulatory affairs, and manufacturing.
- Stay abreast of the latest scientific advancements and emerging technologies in drug discovery.
- Contribute to the development of intellectual property and patent filings.
- Prepare and present research findings to scientific committees, management, and at external conferences.
- Ensure compliance with all laboratory safety regulations and company policies.
- Contribute to the strategic planning and direction of the R&D department.
- Ph.D. in Pharmacology, Medicinal Chemistry, Molecular Biology, or a related life science discipline.
- Minimum of 10 years of post-doctoral research experience in the pharmaceutical industry, with a focus on drug discovery.
- Demonstrated expertise in multiple aspects of the drug discovery pipeline.
- Proven track record of leading successful research projects and delivering key milestones.
- Strong understanding of disease biology and target validation.
- Experience with various drug discovery modalities (e.g., small molecules, antibodies, gene therapy).
- Excellent leadership, communication, and interpersonal skills.
- Proficiency in data analysis and scientific reporting.
- Strong publication record in high-impact, peer-reviewed journals.
- Ability to work effectively in a fast-paced, team-oriented environment.
Principal Pharmaceutical Research Scientist - Drug Discovery
Posted 20 days ago
Job Viewed
Job Description
Responsibilities:
- Design and execute complex research projects for novel drug discovery.
- Identify and validate potential therapeutic targets for various diseases.
- Develop and synthesize small molecule inhibitors or biologics with desired pharmacological profiles.
- Conduct in vitro and in vivo preclinical studies to assess drug efficacy and safety.
- Analyze and interpret experimental data, and troubleshoot complex research challenges.
- Collaborate with cross-functional teams, including chemists, biologists, and clinicians, remotely.
- Stay current with scientific literature, emerging technologies, and competitive research.
- Contribute to the generation of intellectual property (patents) and scientific publications.
- Prepare and present research findings at internal meetings and external scientific conferences.
- Mentor junior scientists and provide technical guidance.
- Ph.D. in Pharmacology, Medicinal Chemistry, Biology, Biochemistry, or a related field.
- Minimum of 10 years of post-doctoral research experience in pharmaceutical or biotechnology R&D.
- Demonstrated success in leading drug discovery programs from target identification to preclinical candidate selection.
- Expertise in relevant therapeutic areas and disease mechanisms.
- Strong knowledge of synthetic chemistry, molecular biology, DMPK, and toxicology principles.
- Proficiency in relevant assay development and high-throughput screening techniques.
- Excellent analytical, problem-solving, and critical thinking skills.
- Exceptional written and verbal communication skills for remote collaboration.
- Proven track record of scientific publications and patent filings.
Principal Pharmaceutical Research Scientist - Drug Discovery
Posted 20 days ago
Job Viewed
Job Description
Principal Pharmaceutical Research Scientist, Drug Discovery
Posted 20 days ago
Job Viewed
Job Description
Principal Pharmaceutical Research Scientist - Drug Discovery
Posted 20 days ago
Job Viewed
Job Description
Key Responsibilities:
- Lead independent research projects focused on the discovery and development of novel therapeutics for unmet medical needs.
- Design and execute complex experiments in medicinal chemistry, pharmacology, or relevant biological assays.
- Identify and characterize potential drug targets, and develop strategies for hit-to-lead optimization.
- Synthesize and characterize novel small molecules or biologics with desired pharmacological properties.
- Interpret experimental data, draw robust conclusions, and present findings at internal and external forums.
- Mentor and guide junior scientists, fostering a collaborative and innovative research environment.
- Stay current with the latest scientific literature, technological advancements, and competitive landscape in pharmaceutical R&D.
- Contribute to the strategic direction of the drug discovery pipeline and participate in intellectual property development.
- Collaborate effectively with cross-functional teams, including chemists, biologists, toxicologists, and clinical researchers, in a remote setting.
- Ensure adherence to all relevant safety, ethical, and regulatory guidelines.
Qualifications:
- Ph.D. in Organic Chemistry, Medicinal Chemistry, Pharmacology, Biochemistry, or a related discipline.
- Minimum of 8 years of post-doctoral research experience in the pharmaceutical or biotechnology industry, with a strong focus on drug discovery.
- Proven track record of successfully contributing to the discovery of drug candidates that have advanced into preclinical or clinical development.
- Extensive experience in synthetic organic chemistry, medicinal chemistry principles, and structure-activity relationship (SAR) studies.
- Proficiency in designing and executing various biological assays, pharmacokinetic (PK), and pharmacodynamic (PD) studies.
- Strong understanding of drug development processes, regulatory requirements, and intellectual property considerations.
- Excellent analytical, critical thinking, and problem-solving skills.
- Exceptional communication, presentation, and interpersonal skills, with demonstrated ability to lead remote teams and collaborate effectively.
- Experience with advanced analytical techniques (e.g., NMR, Mass Spectrometry, HPLC).
Principal Pharmaceutical Research Scientist - Drug Discovery
Posted 20 days ago
Job Viewed
Job Description
Responsibilities:
- Lead and execute cutting-edge research programs focused on the discovery and development of novel therapeutic agents.
- Design, synthesize, and characterize small molecules with potential therapeutic applications, utilizing advanced medicinal chemistry techniques.
- Develop and implement innovative drug discovery strategies, including target identification, lead optimization, and preclinical candidate selection.
- Collaborate with cross-functional teams, including biologists, pharmacologists, and toxicologists, in a remote research environment.
- Oversee the planning and execution of in vitro and in vivo studies to assess compound efficacy, safety, and pharmacokinetic profiles.
- Analyze and interpret complex experimental data, drawing insightful conclusions and making strategic recommendations.
- Prepare high-quality scientific reports, publications, and presentations for internal and external audiences.
- Stay abreast of the latest advancements in pharmaceutical research, drug discovery technologies, and relevant therapeutic areas.
- Contribute to the company's intellectual property strategy through patent filings and innovation disclosures.
- Mentor and guide junior research scientists, fostering a collaborative and high-performing research team.
- Ph.D. in Medicinal Chemistry, Pharmacology, Organic Chemistry, or a related life sciences discipline.
- A minimum of 8-12 years of progressive experience in pharmaceutical R&D, with a strong focus on drug discovery.
- Proven track record of successfully leading drug discovery programs and advancing candidates into preclinical development.
- Extensive experience in medicinal chemistry, including compound design, synthesis, and structure-activity relationship (SAR) analysis.
- Deep understanding of pharmacology, pharmacokinetics, and ADME principles.
- Proficiency with relevant analytical and characterization techniques.
- Excellent problem-solving, critical thinking, and data interpretation skills.
- Strong leadership, project management, and team collaboration abilities.
- Exceptional written and verbal communication skills, with the ability to present complex scientific information effectively.
- Experience working effectively in a remote, collaborative research setting.
Principal Pharmaceutical Research Scientist - Drug Discovery
Posted 20 days ago
Job Viewed
Job Description
Responsibilities:
- Lead and manage complex drug discovery projects from target identification through lead optimization.
- Design and synthesize novel small molecules with potential therapeutic value using advanced medicinal chemistry techniques.
- Develop and validate in vitro and in vivo assays to evaluate compound efficacy, selectivity, and pharmacokinetic properties.
- Interpret complex experimental data, troubleshoot research challenges, and devise innovative solutions.
- Collaborate with biologists, pharmacologists, and toxicologists to advance candidate drugs through the pipeline.
- Prepare high-quality research reports, scientific publications, and regulatory submission documents.
- Stay abreast of the latest scientific literature, technological advancements, and industry trends in drug discovery.
- Mentor and guide junior scientists, fostering a culture of scientific excellence and collaboration.
- Present research findings at internal meetings and external scientific conferences.
- Contribute to the strategic planning and direction of the R&D pipeline.
- Ph.D. in Medicinal Chemistry, Organic Chemistry, Pharmacology, or a closely related field.
- Minimum of 10 years of hands-on experience in pharmaceutical research and drug discovery, with a strong focus on small molecule development.
- Demonstrated expertise in synthetic organic chemistry, structure-activity relationship (SAR) studies, and modern drug design principles.
- Proven success in identifying and advancing drug candidates into preclinical development.
- Experience with various therapeutic areas (e.g., oncology, infectious diseases, CNS) is highly desirable.
- Proficiency in utilizing computational chemistry tools and databases.
- Excellent analytical, problem-solving, and critical thinking skills.
- Exceptional written and verbal communication skills, with a strong publication record.
- Ability to lead scientific projects and manage a team in a remote environment.
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Principal Pharmaceutical Research Scientist - Drug Discovery
Posted 20 days ago
Job Viewed
Job Description
Key Responsibilities:
- Lead research projects focused on identifying and validating novel drug targets for unmet medical needs.
- Design, synthesize, and optimize small molecule drug candidates using medicinal chemistry principles.
- Develop and execute in vitro and in vivo assays to evaluate drug efficacy, safety, and pharmacokinetic properties.
- Analyze complex biological and chemical data, interpret results, and make strategic decisions for project progression.
- Write and review research protocols, reports, and scientific publications.
- Mentor and guide junior scientists, fostering a collaborative and innovative research environment.
- Collaborate with cross-functional teams, including biology, DMPK, toxicology, and clinical development.
- Manage relationships with external research organizations and academic collaborators.
- Present research findings at scientific conferences and to senior management.
- Ensure compliance with all relevant regulatory guidelines and ethical standards.
- Contribute to the intellectual property strategy through patent filings.
Qualifications:
- Ph.D. in Medicinal Chemistry, Pharmacology, Organic Chemistry, or a related field.
- Minimum of 8 years of experience in pharmaceutical drug discovery and development, with a focus on small molecule therapeutics.
- Extensive experience in synthetic organic chemistry and medicinal chemistry techniques.
- Proven track record of leading successful drug discovery projects from target validation to preclinical candidate selection.
- In-depth knowledge of pharmacology, biology, and pharmacokinetic principles.
- Proficiency with relevant software for data analysis and molecular modeling.
- Excellent written and verbal communication skills, with a strong publication record.
- Ability to manage remote research teams and projects effectively.
- Experience relevant to diseases prevalent in regions like **Eldoret, Uasin Gishu, KE** could be an advantage.
Principal Pharmaceutical Research Scientist - Drug Discovery
Posted 18 days ago
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Job Description
Principal Pharmaceutical Research Scientist - Drug Discovery
Posted 18 days ago
Job Viewed
Job Description
Responsibilities:
- Lead and manage drug discovery research projects from concept to candidate selection.
- Design and synthesize novel small molecules or biologics with therapeutic potential.
- Develop and validate in vitro and in vivo assay systems to evaluate drug candidates.
- Conduct detailed pharmacological and pharmacokinetic studies.
- Analyze and interpret complex experimental data, drawing insightful conclusions.
- Collaborate with cross-functional teams, including chemists, biologists, and toxicologists.
- Manage relationships with external research partners and CROs.
- Contribute to the development of intellectual property through patent filings.
- Stay abreast of the latest scientific advancements and emerging technologies in drug discovery.
- Prepare research reports, scientific publications, and presentations.
- Ph.D. in Medicinal Chemistry, Pharmacology, Biochemistry, or a related field.
- Extensive experience in pharmaceutical drug discovery and preclinical development.
- Proven track record of leading successful research projects and bringing compounds forward.
- Expertise in synthetic organic chemistry and/or biological assays.
- Strong understanding of pharmacology, ADME/Tox principles.
- Excellent scientific writing and presentation skills.
- Ability to work independently and effectively in a remote research setting.
- Experience with data analysis software and bioinformatics tools.